Pathology

Shaukat Khanum Pathology Laboratory, one of the nation’s largest and most sophisticated facilities, uses state-of-the-art equipment for all tests, setting a standard for result accuracy and reliability.

The Pathology Laboratory consists of the Anatomic and Clinical Pathology sections including the Blood Bank. With its comprehensive test menu, more than 4 million tests and procedures are performed every year. Both the Laboratory and the Blood Bank are open 24 hours a day, 7 days a week, with Consultant Pathologists available on call round the clock. Read more…

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Pathology Test Panels

Our Pathology services are available at the following locations. Follow the link to see the relevant address and map:

Find below the complete list of tests:

Test NameSample RequiredComments
Analytical Cytometry
Acute Leukemia immunophenotyping on peripheral bloodAspirate, tissue, fluid or blood
CD 34 countBlood or stem cell harvest
CD4/CD8 countBlood
Lymphocyte subset analysis ( chronic leukemia immunophenotyping on peripheral blood, bone marrow & tissueBlood, bone marrow, fluid or tissue
Lymphoma analysisBlood, bone marrow, fluid or tissue
MRD (Minimal Residual Disease) for B-cell ALLBone marrow aspirate
PNH analysisBlood
Blood Bank
Autologous blood collectionProcedure
Blood group + Rh typeEDTA blood
Blood product screen (screened for HBsAg, Anti HCV, HIV, RPR, ALT, T. bilirubin, CBC W/O differential, HB core antibody, NAT & malarial antigen-ICT)5mL serum+6mL EDTA Blood
Cold agglutinin screen or titer Each3mL serum + EDTA blood
Coombs directEDTA blood
Cross match / Unit3mL serum
Fresh frozen plasma (screened)Blood product
Granulocyte apheresisProcedure
Irradiation of blood product (each unit)Blood product
Plasma apheresis (exchange)Procedure
Platelet apheresis - stable for 5 days - filteredProcedure
RBC - packed cell / unit-mL (screened)Blood product
RBC/WBC - packed cell unit + saline wash/filtered (screened)Blood product
Rh (D) Ab. screen3mL serum
Single unit - platelets (screened)Blood product
Stem cell collectionProcedure
Whole blood / unit 500 mL (screened)Blood product
Bone Marrow
Bone marrow - comprehensive (aspiration & trephine biopsies processing & interpretationBone marrow with trephine
Bone marrow - review of stained slides and interpretation up to 5 slidesSlid, block or aspirate
Clinical / Routine Chemistry
IgA - quantitative3mL serum
IgG - quantitative3mL serum
IgG (immunoglobulin G) - CSFCSF
IgG4 subclass3mL serum
IgM - quantitative3mL serum
Magnesium - serum3mL serum
Magnesium - urineUrine
Methotrexate3mL serum
Osmolality serum3mL serum
Osmolality urineUrine
Phosphorous 24 hours urineUrine
Phosphorus3mL serum
Phosphorus urineUrine
Potassium - serum3mL serum
Potassium - spot urineUrine
Potassium 24 hours urineUrine
Prealbumin3mL serum
Protein - 24 hours urineUrine
Protein - CSFCSF
Protein - fluidsFluid
Protein - spot urineUrine
Rheumatoid factor (quantitative)3mL serum
Serum ceruloplasmin3mL serum
Serum transferrin3mL serum
Sodium - serum3mL serum
Sodium - spot urineUrine
Sodium 24 hours urineUrine
TIBC3mL serum
Total bilirubin3mL serum
Total protein - serum3mL serum
Triglycerides3mL serum
UIBC (unsaturated iron biding capacity)3mL serum
Urea nitrogen-24 hoursUrine
Urea nitrogen-spot urineUrine
Uric acid3mL serum
Uric acid 24 hours urineUrine
Uric acid spot urineUrine
Urinary albumin/creatinine ratioUrine
Urinary microalbuminUrine
Urinary protein/creatinine ratioUrine
GGT3mL serum
Glucose - CSFCSF
Glucose - fluidsFluid
Glucose fasting3mL serum12-14 Hours Fasting Required
Glucose random3mL serum
GTT (5 Serum + 5 urine specimens)3mL serum+ urine
HDL cholesterol3mL serum
Albumin3mL serum
Albumin - CSFCSF
Aldolase-serum3mL serum
Alkaline phosphatase (ALP)3mL serum
Alpha-1 acid glycoprotein3mL serum
Alpha-1 antitrypsin3mL serum
ALT3mL serum
AmmoniaEDTA blood
Amylase - serum3mL serum
Amylase - urineUrine
Amylase 24 hours urineUrine
Apolipoprotein A13mL serum
Arterial Blood Gasses (ABG's)Heparinized bloodAvailable only in Hospital
ASO-quantitative (Anti streptolysin O)3mL serum
AST3mL serum
Bence Jones Protein (BJP)Urine
Blood glucose + urine (pH, glucose, protein)-fasting3mL serum+ urine
Blood glucose + urine (pH, glucose, protein)-random3mL serum+ urine
Blood Urea Nitrogen (BUN)3mL serum
C33mL serum
C43mL serum
Calcium - serum3mL serum
Calcium - spot urineUrine
Calcium 24 hours urineUrine
Calcium - corrected3mL serum
Cardiac profile (LDH, CK, AST, CKMB)3mL serum
Chloride - serum3mL serum
Chloride - urineUrine
Chloride 24 hours urineUrine
Cholesterol3mL serum12-14 Hours Fasting Required
CK3mL serum
CK-MB3mL serum
CO23mL serum
CO2 urea and electrolytes (Na, K, Cl, urea, creatinine)3mL serum
C-Reactive Protein High Sensitive (CRP-HS)3mL serum
Creatinine - 24 hours urineUrine
Creatinine - serum3mL serum
Creatinine clearance3mL serum+ urine
Creatinine urineUrine
CRP (quantitative)3mL serum
CSF testing - comprehensive (includes glucose, protein, cell count & differential and culture)CSF
Direct bilirubin3mL serum
Electrolytes (Na, K, Cl)3mL serum
Ionized calcium3mL serum
Iron3mL serum
Kappa light chain (bound and free)3mL serum
Kappa , lambda light chain (bound and free) profile included ratio3mL serum
LactateSodium citrated blood
Lactate - CSFCSF
Lambda light chain (bound and free)3mL serum
LDH - CSFCSF
LDH - fluidsFluid
LDH - serum3mL serum
LFT (TP, ALP, ALB, T.BILI, ALT, AST, GGT, A/G ratio)3mL serum
Lipase3mL serum
Lipid profile (TRIG, CHOL, LDL, HDL, VLDL)3mL serum12-14 Hours Fasting Required
Cyto Pathology
Cytopathology per slide for patient (stained/unstained)Slide from outside
Fluids, (washings, effusions, cyst fluid, CSF, brushings, discharges, sputum & urine), concentration and smears screening and interpretation (if cell block needed then charges X 2)Fluid
FNA by clinician (attended by cytotechnologist), interpretation by pathologist (including cell block)FNA
FNA by pathologist, preparation and interpretation (including cell block)FNA
FNA (attended by cytotechnologist), on site evaluation and preliminary diagnosisFNA
Outside unstained FNA slides/FNA material (including cell block)Slide from outside
Review of slides (upto 5)Slide from outside
Semen analysisSemen sample in hospitalAvailable only at SKMCH & RC
Gynaecological, cervical or vaginal smearsSlide from outside
Review of gynaecological cervical or vaginal reported smearsSlide from outside
Thin prep Gyn cytologySample
from cervix
Sample collection by gyneacologist in recommended collection device
Haematology
Activated Partial Thromboplastin Time (APTT)3mL blood
Bleeding time (IVY's method)ProcedureAvailable only in Hospital
CBC - special for dengue3mL blood
CBC + auto differential (5 parts) includes Hb3mL blood
CBC + manual differential (5 parts) includes Hb3mL blood
CBC without differential includes Hb3mL blood
Cell count + differentialBody fluid, CSF
Clotting inhibitors/anticoagulants; Antithrombin III activity3mL blood
Clotting; Factor V (ACG/proaccelerin), labile factor3mL blood
Clotting; Factor VII (proconvertin, stable factor)3mL 3.2% sodium citrate tube(coagulation)Whole Blood
Clotting; Factor XI (PTA)3mL 3.2% sodium citrate tube(coagulation)Whole Blood
Clotting; Factor XII (hageman)3mL 3.2% sodium citrate tube(coagulation)Whole Blood
D-Dimer3mL blood
Eosinophil count (blood, nasal, sputum and urine)Blood, sputum, urine, nasal aspirate
ESR (Erythrocytes Sedimentation Rate)1.5-mL blood
Factor IX3mL blood
Factor VIII3mL blood
Factor X3mL blood
Fibrinogen3mL blood
Fibrinogen Degradation Product (FDP)3mL blood
Filaria parasite (filariasis)3mL bloodCertain of the Microfilariae parasites have a nocturnal periodicity, and the blood specimen should be taken at night between 10 p.m. and 2 a.m.
G-6-PD qualitativeEDTA blood
Hematocrit (HCT)3mL blood
Hemoglobin (Hb)3mL blood
Immature Platelet Fraction (IPF%)3.0ml EDTAWhole Blood
Lupus anticoagulant3mL 3.2% sodium citrate tube(coagulation)Whole Blood
Malaria antigen ICTEDTA blood
Malarial Parasites ( MP )EDTA blood
Protein C3mL blood
Protein S-Ac3mL 3.2% sodium citrate tube(coagulation)Whole Blood
Prothrombin Time (PT/INR)3mL blood
RBC morphology3mL blood
Reticulocyte count3mL blood
Reticulocyte Hemoglobin Equivalent (Ret-He)3.0ml EDTAWhole Blood
Sickle cell screenEDTA blood
Thrombin time3mL blood
Histopathology
Mortuary body storage per dayDead body
DecalcificationBone biopsy
Frozen section (single specimen) by appointment Tissue sample
Histochemical stains, per slide (reticulum, PAS, GMS, mucicarmine, perls's Prussian, alcian blue, congo red, oil red, PASD, MGP & trichrome, etc...)Block
Histopathology (gross & microscopy) for prostate biopsiesTissue
Histopathology (gross microscopy & immunohistochemistry stains)Tissue
Histopathology (gross, microscopy & immunochemistry stains)Tissue
Histopathology comprehensive review - referred slides & blocks (over 10) per slides & blocksBlocks + slide
Histopathology comprehensive review - referred slides & blocks (upto 10 slides & blocks)Blocks + slide
Histopathology consultations - referred blocks / slides (upto 5 blocks)Blocks/slides
Histopathology per slide(H&E) /block for patientslide+ blocks
Immunocytochemistry (each antibody)Paraffin block
Immunofluoresence study, each antibody; direct method Tissue sample
Liver, kidney or muscle biopsy (including immunohistochemistry) Tissue sample
Renal biopsy - comprehensive including histology, special stain & immunofluorescenceTissue
Medical Cytogenetics
ATM (11q22) deletion by Fluorescence In-Situ Hybridization, FISHBone marrow/ peripheral bloodGreen Top vacuum tube (sodium/lithium heparin) 2-3 mL (BM),   3-4 mL (PB)
BCR-ABL t(9;22)(q34;q11.2) by Fluorescence In Situ Hybridization (FISH)Blood or bone marrow
Chromosome analysis, for congenital disorders, bloodBlood
FISH, PML/RARA  t(15;17)(q24;q21)Bone marrow/ peripheral bloodGreen Top vacuum tube (sodium/lithium heparin) 2-3 mL (BM),   3-4 mL (PB)
FISH, Trisomy 12Bone marrow/ peripheral bloodGreen Top vacuum tube (sodium/lithium heparin) 2-3 mL (BM),   3-4 mL (PB)
MLL (11q23) gene rearrangement, FISHBlood or bone marrow
p53 (17p13) deletion by Fluorescence In Situ Hybridization, FISHBone marrow/ peripheral bloodGreen Top vacuum tube (sodium/lithium heparin) 2-3 mL (BM),   3-4 mL (PB)
TEL/AML t(12;21)(p13;q22) by Fluorescence In Situ Hybridization (FISH)Blood or bone marrow
Microbiology
Giardia and Cryptosporidium antigen detection in stoolStool
Chlamydia Trachomatis (CT) and Neisseria Gonorrhea (NG) detection via geneXpertUrine
Clostridium Difficile (toxigenic) detection via geneXpertStool
Cryptococcus antigen in CSF / serumCSF, serum
Cryptosporidium stain from stoolStool
Crystals in synovial fluidFluid
Culture and sensitivity (automated) for TBSputum + other
Culture blood5 mL blood
Culture-fungal, includes microscopy and culture on specialized media (dermatophyte 6 test medium and sabraud dextrose agar)Other sample
Culture-others (aspirates, ascitic fluids)Other sample
Culture-sputumSputum
Culture-stool, includes microscopy for WBC's RBC's and trophozoites, culture for Salmonella and Shigella (to species level)Stool
Culture-throat swabSwab
Culture-urine, includes microscopy and cultureUrine
Culture-wound swabSwab
Faecal occult bloodStool
Food testingFood
Fungal screen - KOH preparationtissue, fluid, respiratory samples
Gram stain all sites, where requestedOther sample
H. pylori antigen detection in stoolStool
India ink stain (Cryptococcus sp)CSF
Legionella antigen in urineUrine
Legionella testing (filtration, concentration & culture on specialized media to grow and identify environmental and clinical isolates5 water sample
Mycobacteria routine stain (ZN for AAFB)Sputum
Mycobacterium tuberculosis (TB) gold assay -IGRA5 mL blood
Mycobacterium tuberculosis detection via Xpert MTB-Rif assayFluid, respiratory samples
pH (body fluids)Other sample
Specific gravity body fluidsFluid
Sputum/broncho alveoli washout (routine culture & Legionella)Sputum
Stool - Campylobacter cultureStool
Stool - microscopy and identification of ova, cysts & parasitesStool
Stool - microscopy for RBC's & WBCsStool
Stool - Rotavirus testingStool
Stool - typing of Salmonella and ShigellaStool
Stool-Clostridium difficile toxin A screen (using monoclonal Abs)Stool
Streptococcus pneumonia antigen detection in urine and CSFUrine, CSF
Urinalysis - chemistry complete (glucose, bilirubin, ketones, specific gravity, blood, pH, protein, urobilinogen, nitrite, leukocytes) Urine
Urinalysis, microscopy complete (WBC, RBC, epithelial cells, casts, bacteria, crystals, mucous)Urine
Urine (pH, glucose, protein) onlyUrine
Urine pregnancy testUrine
Urine routine, chemistry & microscopy, glucose, ketones, bilirubin, pH, blood, specific gravity, protein, urobilinogen, nitrite & leucocytes, micro report includes RBC's, WBC's, epithelial cells, casts, bacteria & crystalsUrine
Water testingWater
Molecular Biology
FISH, ALK (2p23) gene rearrangementBlock
FISH, EGFR amplificationBlock
FISH, Ewing's sarcomaBlock
FISH, FOXO1 (13q14) gene rearrangementBlock
FISH, HER 2/NeuBlock
FISH, MDM2 gene amplificationBlock
FISH, N-MYCBlock
FISH, Oligodendrioglioma (1p/19q)Block
FISH, Synovial sarcomaBlock
PCR for HCV genotyping5mL serum
HLA DRBEDTA blood
IL28B Polymorphism by PCR (real time)Blood
PCR BCR - ABL quantitative (real time)EDTA blood
PCR Cytomegalovirus (CMV) quantitative (real time)5mL serum
PCR for Adenovirus DNA (real time)Whole blood, CSF, BAL, biopsies
PCR for BK DNA (real time)Whole blood, urine , plasma
PCR for BRAF mutation detection (real time)Block
PCR for Clostridium Difficile (toxin B) quantitative (real time)Stool
PCR for EBV DNA (real time)Whole blood, CSF, BAL, biopsies
PCR for HSV1, HSV2 and VZV (real time)CSF, plasma ,BAL
PCR for JAK2 mutation detection (real time)Blood
PCR for KRAS mutation detection (real time)Block
PCR for MTB drug resistancePulmonary and extra pulmonary
PCR for MTB drug resistanceFluids
PCR HBV qualitative (real time)5mL serum
PCR HBV quantitative (real time)5mL serum
PCR HCV qualitative (real time)5mL serum
PCR HCV quantitative (real time)5mL serum
PCR HDV qualitative5mL serum
PCR HIV quantitative (real time)EDTA blood
PCR IDH1 mutation detection (real time)Block
PCR Influenza A and B detection (real time)Swab
PCR Mycobacterium species from culture materialCulture material
PCR Mycoplasma genitalium detection by real timeSwab
PCR RT BCR - ABL qualitativeEDTA blood
PCR viral transplant panel (EBV, BK, Adenovirus) (real time)Whole blood, CSF, BAL, biopsies
Total HLA typingEDTA blood
EGFR -mutation detection in lung cancer by real time PCRBlock
Total HLA typing minus DREDTA blood
Special Chemistry
17 hydroxy progesterone3mL serum
25 hydroxy vitamin D3mL serum
ACTHEDTA blood
AFP3mL serum
Aldosterone3mL serum
Anti cardiolipin Ig G,A,M3mL serum
Anti CCP3mL serum
Anti gliadin IgA3mL serum
Anti gliadin IgG3mL serum
Anti HAV-IgG3mL serum
Anti HAV-IgM3mL serum
Anti HB core IgM3mL serum
Anti Hbe3mL serum
Anti HBs3mL serum
Anti HCV3mL serum
Anti HDV (total)3mL serum
Anti HIV3mL serum
Anti Measles IgG3mL serum
Anti Measles IgM3mL serum
Anti Mumps IgG3mL serum
Anti Mumps IgM3mL serum
Anti phospholipid IgG3mL serum
Anti phospholipid IgM3mL serum
Anti thyroglobulin3mL serum
Anti tissue transglutaminase IgA3mL serum
Anti tissue transglutaminase IgG3mL serum
Anti tissue transglutaminase IgG & IgA (combined)3mL serum
Anti TPO3mL serum
Anti Varicella Zoster IgG3mL serum
Anti Varicella Zoster IgM3mL serum
Anti-mitochondrial antibodies3mL serum
Antinuclear Antibodies (ANA) by immunofluorescence3mL serumExcept Saturday & Sunday
Aspergillus (galactomannan) antigen3mL serum
Beta 2 microglobulin3mL serum
Beta D glucan3mL serum
Beta HCG (serum pregnancy test)3mL serum
Beta HCG free (tumor marker)3mL serum
Brucella antibodies3mL serum
B-Type Natriuretic Peptide (BNP)3-mL blood
c&p ANCA3mL serum
CA-1253mL serum
CA-15.33mL serum
CA-19.93mL serum
Calcitonin3mL serum
c-ANCA (anti proteinase-3)3mL serum
Carbamazepine3mL serum
CEA3mL serum
Cortisol3mL serum
Cortisol 24 hours urine24 Hr. urineExcept Sun
c-Peptide3mL serum
Cyclosporine, bloodEDTA blood
Cytomegalovirus IgG3mL serum
Cytomegalovirus IgM3mL serum
Dengue IgG - antibody3mL serum
Dengue IgM - antibody3mL serum
Dengue NS1 antigen3mL serum
DHEA - SO43mL serum
Digoxin3mL serum
Drug of abuse screening, urineUrine
dsDNA antibodies by Crithidia IFA3mL serumExcept Sat & Sun
Echinococcus antibody IgG3mL serum
ENA/ANA profile3mL serum
Erythropoietin3mL serum
Estradiol3mL serum
Estriol - free3mL serum
Faecal calprotectinStool
Ferritin3mL serum
Folate3mL serum
Folate, red cellEDTA bloodAvailable only in hospital
Free T33mL serum
Free T43mL serum
FSH3mL serum
Glycohemoglobin (HbA1C)EDTA blood
Hb - ElectrophoresisEDTA blood
HB core antibody3mL serum
HBeAg3mL serum
HBsAg3mL serum
HBsAg quantitative3mL serum
Helicobacter Pylori IgG3mL serum
Hepatitis E (HEV) IgG3mL serum
Hepatitis E (HEV) IgM3mL serum
Herpes I & II IgG3mL serum
Herpes I & II IgM3mL serum
HGH3mL serum
Homocysteine3mL serum
IgE - total3mL serum
Immunofluorescence antibody panel for AMA,ASMA and ANA3mL serum
Immunotyping, serum3mL serum
Immunotyping, urineUrine
Insulin3mL serum
Insulin Like Growth Factor - 1 (IGF-1)3mL serum
LH3mL serum
Metanephrine and NormetanephrinePlasma
Mono spot (infectious mono)3mL serum
Neonatal TSH3mL serum
p-ANCA (anti MPO)3mL serum
Parvovirus B19 antibody IgG3ml serum
Parvovirus B19 antibody IgM3ml serum
Phenytoin3mL serum
Progesterone3mL serum
Prolactin3mL serum
PSA3mL serum
PTH-intact3mL serum
ReninEDTA bloodAvailable only in hospital
Respiratory Syncytial Virus (RSV) antibodies IgG3mL serum
Respiratory Syncytial Virus (RSV) antibodies IgM3mL serum
RPR with titer3mL serum
Rubella IgG3mL serum
Rubella IgM3mL serum
Serum protein-electrophoresis3mL serum
Sex Hormone Binding Globulin (SHBG)3mL serum
T33mL serum
T43mL serum
Tacrolimus, bloodEDTA blood
Testosterone3mL serum
Thyroglobulin3mL serum
Thyroglobulin, tumor marker3mL serum
Thyroid profile (T3, T4, TSH)3mL serum
Thyroid screening (free T4, TSH)3mL serum
Thyroid uptake3mL serum
TORCH profile3mL serum
Toxoplasma IgG3mL serum
Toxoplasma IgM3mL serum
TPHA3mL serum
Troponin I3mL serum
TSH3mL serum
Typhoid IgG antibody3mL serum
Typhoid IgM antibody3mL serum
Urinary beta-2-microglobulinUrine
Urine protein electrophoresisUrine
Valproic Acid3mL serum
Vancomycin3mL serum
Vitamin B-123mL serum
VMA (Vanillylmandelic Acid), 24 hour urine3-mL blood
Widal test3mL serum
Online Donation Box

Donate any amount of your choice or be an official online fundraiser of Shaukat Khanum Memorial Cancer Hospital and Research Centre by following these simple guide lines: Step-1: Sign up http://bit.ly/2kJuvwn Step-2: Create your fundraising page Step-3: Donate and pass it on to your friends If we all do a little, we can do a […]


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Donate Now

Many young innocent lives are being saved at Shaukat Khanum Memorial Cancer Hospital and Research Centre. Last year, your Zakat made it possible to treat almost 75% of our patients for free. This year we need 5.5 billion rupees to help those who cannot afford to pay for their own treatment. While the revenue from […]


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Press Release

Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&RC) celebrated its 22nd birthday in a colorful event organized by Shaukat Khanum Tigers’ Club. Nearly 700 school children from various cities across Pakistan participated in the event. A large gathering showed the enthusiasm of children for their passion to fight against cancer. Children from different schools […]


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Events

Keep yourself updated with our latest events, held throughout the year and all around the world. Your participation in these events directly supports our mission of fighting cancer.   Upcoming Events Previous Events Groundbreaking of Shaukat Khanum Memorial Cancer Hospital and Research Centre, Karachi December 29, 2016 22nd Birthday Celebrations – Annual Card Competition December, […]


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